Neuropilin 1 抗体 (AA 700-900)
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Quick Overview for Neuropilin 1 抗体 (AA 700-900) (ABIN7864581)
抗原
See all Neuropilin 1 (NRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 700-900
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原理
- NRP1 / Neuropilin-1 Antibody
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特异性
- Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa700-900) of human NRP1 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Neuropilin 1 (NRP1) (AA 646-814) antibody
NRP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 646-814) antibodyNRP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Neuropilin 1 (NRP1) (AA 22-131) antibodyNRP1 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Neuropilin 1 (NRP1) (AA 21-250) antibodyNRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) antibodyNRP1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 722-750), (C-Term) antibodyNRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22995 unconjugated
anti-Neuropilin 1 (NRP1) (AA 722-750) antibodyNRP1 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 45-59) antibodyNRP1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5B1E11 unconjugated
anti-Neuropilin 1 (NRP1) antibodyNRP1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB180 unconjugated Recombinant Antibody
anti-Neuropilin 1 (NRP1) (AA 504-827) antibodyNRP1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Neuropilin 1 (NRP1)
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别名
- NRP1
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背景
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A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD304, Neuropilin-1, Neuropilin1, NP1, NPN1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R
Human placenta|kidney or lymph node.|testis
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分子量
- 130kDa
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基因ID
- 8829, 131704
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UniProt
- O14786
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途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
抗原
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