PIK3CD 抗体 (AA 520-720)
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Quick Overview for PIK3CD 抗体 (AA 520-720) (ABIN7860358)
抗原
See all PIK3CD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 520-720
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原理
- PIK3CD Antibody
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特异性
- Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85a and p85b), each possessing one SH3 and two SH2 domains. Various p110 forms have been identified. p110a and p110b interact with p85a, and p110a has also been shown to interact with p85b in vitro. It has been shown to bind p85a and b, but it apparently does not phosphorylate these subunits. p110d has the capacity to autophosphorylate and results in the nearly complete inactivation of the lipid kinase activity. Interestingly, p110g does not interact with the p85 subunits and has been shown to be activated by a and bg heterotrimeric G proteins. Two p110d isoforms have been identified and are widely expressed. Isoform 1 is expressed predominantly in leukocytes while isoform 2 is expressed in normal thymus, lung and spleen tissues.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human PIK3CD protein (around aa 520-720) (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 687-717), (C-Term) antibody
PIK3CD 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB1707 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 774-1044) antibodyPIK3CD 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 85-114), (N-Term) antibodyPIK3CD 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB11627 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (pTyr524) antibodyPIK3CD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 51-150) antibodyPIK3CD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 150-250) antibodyPIK3CD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (N-Term) antibodyPIK3CD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (pTyr524) antibodyPIK3CD 适用: 人 DB 宿主: 兔 Polyclonal RB13317 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (pTyr485) antibodyPIK3CD 适用: 人 DB 宿主: 兔 Polyclonal RB41429 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (N-Term) antibodyPIK3CD 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- PIK3CD (Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD))
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别名
- PIK3CD
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背景
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5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, APDS, GRB1, IMD14, p110delta, p110dp85a, p85-ALPHA, Phosphoinositide 3 kinase B, Phosphoinositide 3 kinase C, Phosphoinositide 3 kinase catalytic delta polypeptide, Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta, PI3K-delta, PIK3R1, PtdIns 3 kinase p110, PtdIns 3 kinase subunit p110 delta, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit p110-delta
lymph node or tonsil|THP1 cells. Human spleen
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分子量
- 119/33kDa
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基因ID
- 5293, 518451
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UniProt
- O00329
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途径
- BCR Signaling, Warburg Effect
抗原
-
