RALGAPB 抗体 (AA 500-700)
The 小鼠 单克隆 anti-RALGAPB antibody (Clone ABCB1-9307) (ABIN7865440) specifically detects RALGAPB in WB 和 IHC.
The antibody is reactive with 人 samples.
产品编号 ABIN7865440
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for RALGAPB 抗体 (AA 500-700) (ABIN7865440)
抗原
RALGAPB
(Ral GTPase Activating Protein, beta Subunit (Non-Catalytic) (RALGAPB))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This RALGAPB antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
克隆位点
ABCB1-9307
-
-
抗原表位
- AA 500-700
-
原理
- p170 / MDR1 / CD243 Antibody
-
特异性
- Cells selected for resistance to a single cytotoxic drug may become crossresistant to a broad range of drugs with different structures and cellular targets. This phenomenon is called multiple drug resistance (MDR). MDR proteins (Mdrs) are members of a highly conserved superfamily of ATP-binding cassette transport proteins. Mdr-1 is an apical transmembrane protein that is an integral part of the blood-brain barrier and functions as a drug-transport pump transporting a variety of drugs from the brain back into the blood. The Mdr-1 gene is known as ABCB1 and is located on human chromosome 7q21.12. The mouse homolog of Mdr-1 is known as Mdr-3. Interestingly, a murine protein by the name of Mdr-1 exists and is encoded by the murine Abcb1b gene, but it is not homologous with human Mdr-1.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment (around aa500-700) of human ABCB1 protein (exact sequence is proprietary)
-
亚型
- IgG2a, kappa
-
-
anti-Ral GTPase Activating Protein, beta Subunit (Non-Catalytic) (RALGAPB) (AA 1025-1075) antibody
RALGAPB 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- RALGAPB (Ral GTPase Activating Protein, beta Subunit (Non-Catalytic) (RALGAPB))
-
别名
- p170
-
背景
-
ABC20, ABCB1, ATP-binding cassette sub-family B member 1, CD243, CLCS, Colchicin sensitivity, Doxorubicin resistance, GP170, Multidrug resistance protein 1 (MDR1), P-glycoprotein 1 (PGY1)
hPBL or Jurkat cells. Human adrenal gland or kidney.
-
分子量
- 170kDa
-
基因ID
- 5243, 489033
-
UniProt
- P08183
抗原
-
You are here:
