PAX8 抗体 (AA 50-300)
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北京 101111
Quick Overview for PAX8 抗体 (AA 50-300) (ABIN7860279)
抗原
See all PAX8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-300
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原理
- PAX8 (Renal Cell Marker) Antibody
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特异性
- Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa50-300) of human PAX8 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Paired Box 8 (PAX8) antibody
KO Validated PAX8 适用: 人 WB, IHC, IF, IHC (p), ICC, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人, 犬 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal PAX8-1492 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1A1D3 unconjugated
anti-Paired Box 8 (PAX8) (AA 1-450) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal PAX8-1491 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Paired Box 8 (PAX8) (AA 141-250) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G11 unconjugated
anti-Paired Box 8 (PAX8) (N-Term) antibodyVerified PAX8 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 300-450) antibodyPAX8 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3E6B3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PAX8 (Paired Box 8 (PAX8))
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别名
- PAX8
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背景
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Paired box 8, Paired box gene 8, paired box homeotic gene 8, Paired box protein Pax-8, Paired domain gene 8, PAX8
HeLa or Raji cells. Human renal cell carcinoma (RCC) or ovarian serous carcinoma.
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分子量
- 62kDa
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基因ID
- 7849, 469728
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UniProt
- Q06710
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途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
抗原
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