Elastase 3A 抗体 (AA 50-250)
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北京 101111
Quick Overview for Elastase 3A 抗体 (AA 50-250) (ABIN7860247)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-250
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原理
- CELA3A / Chymotrypsin like elastase 3A Antibody
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特异性
- Elastases belong to a subfamily of serine proteases that function to catalytically hydrolyze a wide variety of proteins. Elastase-3A, also known as ELA3A or ELA3, is a 270 amino acid protein that belongs to the elastase family and acts as an alanine-specific protease. Secreted as a zymogen from the pancreas, Elastase-3A functions as a digestive enzyme in the intestine that participates in metabolic degradation pathways by preferentially cleaving proteins that have alanine residues. In addition, Elastase-3A is thought to play a role in the metabolism and transport of cholesterol molecules in the intestine. Altered expression of Elastase-3A may be associated with pancreatic ductal carcinoma, a highly fatal cancer of the pancreatic ducts
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa50-250) of human CELA3A protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Elastase 3A (ELA3A)
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别名
- CELA3A
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背景
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ELA3, ELA3A
Human pancreas or pancreatic cancer.
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分子量
- 29 kDa
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基因ID
- 10136
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UniProt
- P09093
抗原
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