CD207 抗体 (AA 50-250)
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Quick Overview for CD207 抗体 (AA 50-250) (ABIN7864472)
抗原
See all CD207 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-250
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原理
- Langerin / CD207 (Marker of Langerhans Cells) Antibody
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特异性
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa50-250) of human Langerin protein (exact sequence is proprietary)
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亚型
- IgG
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anti-CD207 Molecule, Langerin (CD207) (AA 155-328) antibody
CD207 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1C5A1 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 1-328) antibodyCD207 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 229-312) antibodyCD207 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) antibodyCD207 适用: 人, Non-Human Primate ELISA, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal LGRN-1821 unconjugated
anti-CD207 Molecule, Langerin (CD207) antibodyCD207 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 12D6 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 161-260) antibodyCD207 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 1-328) antibodyCD207 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 26-44) antibodyCD207 适用: 小鼠 WB, IHC, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 ELISA 宿主: 兔 Monoclonal LGRN-3136R unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CD207 (CD207 Molecule, Langerin (CD207))
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别名
- Langerin
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背景
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C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin
Human skin.
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分子量
- 48kDa
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基因ID
- 50489, 199731
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UniProt
- Q9UJ71
抗原
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