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Progesterone Receptor 抗体 (AA 483-571)

The 小鼠单克隆 anti-Progesterone Receptor antibody is suitable to detect Progesterone Receptor in samples from 人. It has been validated for IHC.

产品编号 ABIN7863235

发货至: 中国

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Quick Overview for Progesterone Receptor 抗体 (AA 483-571) (ABIN7863235)

抗原

See all Progesterone Receptor (PGR) 抗体

Progesterone Receptor (PGR)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Progesterone Receptor antibody is un-conjugated

应用范围

Immunohistochemistry (IHC)

克隆位点

PGR-3817

Discover our top product PGR Primary Antibody

抗原表位
16

15

15

15

13

10

10

10

8

8

7

7

6

5

5

5

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 483-571

原理

Progesterone Receptor (Marker of Progestin Dependence) Antibody

特异性

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.

纯化方法

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

免疫原

Recombinant fragment (around aa 483-571) of human PGR (exact sequence is proprietary)

亚型

IgG2b, kappa
anti-Progesterone Receptor (PGR) (AA 1-110) antibody
PGR 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D10 unconjugated

anti-Progesterone Receptor (PGR) (AA 166-411) antibody
PGR 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E9F2 unconjugated

anti-Progesterone Receptor (PGR) (AA 166-411) antibody
PGR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E4B9 unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 小鼠 Monoclonal 188 unconjugated

anti-Progesterone Receptor (PGR) (AA 1-250) antibody
PGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 501-600) antibody
PGR 适用: 人 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR 适用: 激素 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer400) antibody
PGR 适用: 人, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer294) antibody
PGR 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

Progesterone Receptor (PGR)

别名

Progesterone Receptor

背景

NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor form A, Progesterone receptor form B
Human breast cancers.

分子量

PR-A (81kDa) and PR-B (116kDa).

基因ID

5241, 2905

UniProt

P06401

途径

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration