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CD56 抗体 (AA 400-650)

The 小鼠 单克隆 anti-CD56 antibody (Clone NCAM-7521) (ABIN7864364) specifically detects CD56 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7864364
发货至: 中国
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Room 801-803
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Quick Overview for CD56 抗体 (AA 400-650) (ABIN7864364)

抗原

See all CD56 (NCAM1) 抗体
CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD56 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

NCAM-7521
  • 抗原表位

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    AA 400-650

    原理

    CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody

    特异性

    This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa400-650) of human NCAM1 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

    别名

    CD56

    背景

    NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule

    Human cerebellum|pancreas or neuroblastoma.

    分子量

    145 and 125kDa|180

    基因ID

    4684, 503878

    UniProt

    P13591, P13592
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