MX1 抗体 (AA 400-592)
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Quick Overview for MX1 抗体 (AA 400-592) (ABIN7860081)
抗原
See all MX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 400-592
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原理
- MX1 / MX dynamin like GTPase 1 Antibody
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特异性
- The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-a/IFN-b. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-a/IFN-b, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa400-592) of human MX1 protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-Myxovirus Resistance Protein 1 (MX1) (Internal Region) antibody
MX1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 80-342) antibodyMX1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 7-172) antibodyMX1 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (C-Term) antibodyMX1 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 豚鼠, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 68-303) antibodyMX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 1-662) antibodyMX1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 1-662) antibodyMX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 43-308) antibodyMX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (AA 80-342) antibodyMX1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Myxovirus Resistance Protein 1 (MX1) (C-Term) antibodyMX1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- MX1 (Myxovirus Resistance Protein 1 (MX1))
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别名
- MX1
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背景
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Human interferon regulated resistance GTP binding protein MXA, IFI78K, Interferon induced GTP binding protein Mx1, Interferon inducible protein p78, Interferon regulated resistance GTP binding protein MxA, MxA, Myxoma resistance protein 1, Myxovirus (influenza virus) resistance 1 interferon inducible, N-terminally processed
breast cancer or colon cancer tissues.|Human spleen|Tonsil
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分子量
- 72kDa
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基因ID
- 4599, 517307
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UniProt
- P20591
抗原
-
