GBP1 抗体 (AA 400-592)
Our Local Distributor
北京 101111
Quick Overview for GBP1 抗体 (AA 400-592) (ABIN7860075)
抗原
See all GBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 400-592
-
原理
- GBP1 Antibody
-
特异性
- GBP1 (guanylate binding protein 1) is a 592 amino acid protein member of the GTPase protein family and is able to bind specifically to guanine nucleotides such as GMP, GDP and GTP. GMP is hydrolyzed to GTP in two consecutive cleavage steps, both of which are carried out by GBP1. Localized to the cytoplasm, GBP1 is expressed in endothelial cells of the vascular system and is induced by IFN-g during macrophage induction. GBP1 is thought to regulate the expression of MMP-1, which mediates the proliferation and invasiveness of endothelial cells. GBP1 plays a key role in regulating inflammatory cytokines and provides protection against vesicular stomatitis and encephalomyocarditis viruses. GBP1 expression is highly induced in the vessels of skin diseases such as psoriasis and Kaposi s sarcoma, making it a novel cellular activation marker that characterizes inflammatory cytokines of endothelial cells.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment (around aa400-592) of human GBP1 protein (exact sequence is proprietary)
-
亚型
- IgG1, kappa
-
-
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (AA 1-593) antibody
GBP1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (AA 1-592) antibodyGBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (AA 1-592) antibodyGBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (AA 383-592) antibodyGBP1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (AA 1-592) antibodyGBP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (AA 1-592) antibodyGBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (C-Term) antibodyGBP1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) antibodyGBP1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) (Internal Region) antibodyGBP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Binding Protein 1, Interferon-Inducible (GBP1) antibodyGBP1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))
-
别名
- GBP1
-
背景
-
GTP binding protein 1, Guanine nucleotide binding protein 1, Guanylate binding protein 1 interferon inducible 67 kDa, HuGBP1, Interferon induced guanylate binding protein 1, OTTHUMP00000012352
Human colon or cerebral cortex tissue.
-
分子量
- 67kDa
-
基因ID
- 2633, 62661
-
UniProt
- P32455
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-
