Fascin 抗体 (AA 350-400)
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北京 101111
Quick Overview for Fascin 抗体 (AA 350-400) (ABIN7863398)
抗原
See all Fascin (FSCN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 350-400
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原理
- Fascin-1 (Reed-Sternberg Cell Marker) Antibody
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特异性
- Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin s disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa350-400) of human FSCN1 protein (exact sequence is proprietary)
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亚型
- IgG2a, kappa
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anti-Fascin (FSCN1) antibody
FSCN1 适用: 人, 大鼠 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal FSCN1-418 unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal FSCN1-417 unconjugated
anti-Fascin (FSCN1) (AA 11-110) antibodyFSCN1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal FSCN1-416 unconjugated
anti-Fascin (FSCN1) (AA 394-493) antibodyFSCN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (pSer39) antibodyFSCN1 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 322-350) antibodyFSCN1 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 2-187) antibodyFSCN1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) antibodyKD Validated FSCN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2525 unconjugated Recombinant Antibody
anti-Fascin (FSCN1) (AA 322-350) antibodyFSCN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19501 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Fascin (FSCN1)
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别名
- Fascin-1
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背景
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55 kDa actin-bundling protein, FAN1, Fascin homolog 1, Fascin1, FSCN1, HSN, p55, Singed (Drosophila) like (sea urchin fascin homolog like), SNL
HeLa, MCF-7, Ovarian or Testicular Carcinoma., PC-3 or BEWO cells. Hodgkin s lymphoma
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分子量
- 55kDa
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基因ID
- 6624, 118400
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UniProt
- Q16658
抗原
-
