Vitamin D-Binding Protein 抗体 (AA 35-175)
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Quick Overview for Vitamin D-Binding Protein 抗体 (AA 35-175) (ABIN7862887)
抗原
See all Vitamin D-Binding Protein (GC) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-175
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原理
- GC Vitamin D Binding Protein Antibody
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特异性
- Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 35-175) of human GC protein (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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anti-Vitamin D-Binding Protein (GC) (AA 209-401) antibody
GC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 395-474) antibodyGC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 209-401) antibodyGC 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 17-256) antibodyGC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (Internal Region) antibodyVerified GC 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 164-213) antibodyGC 适用: 人, 大鼠, 小鼠, 马, 犬, Pig, Cow, 猴, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 1-474) antibodyGC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 1-474) antibodyGC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 209-394) antibodyGC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Vitamin D-Binding Protein (GC) (AA 18-30) antibodyVerified GC 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Vitamin D-Binding Protein (GC)
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别名
- GC Vitamin D Binding Protein
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背景
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DBP/GC, Gc globulin, GRD3, Group specific component vitamin D binding protein, hDBP, VDB, VDBG, VDBP, Vitamin D binding alpha globulin, Vitamin D-binding protein
Human liver, kidney or pancreas.
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分子量
- 53kDa.
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基因ID
- 2638, 418497
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UniProt
- P02774
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途径
- Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process
抗原
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