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MYCN 抗体 (AA 335-463)

The 小鼠 单克隆 anti-MYCN antibody is suitable to detect MYCN in samples from 人. It has been validated for ELISA 和 FACS.
产品编号 ABIN7859943
发货至: 中国
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Quick Overview for MYCN 抗体 (AA 335-463) (ABIN7859943)

抗原

See all MYCN 抗体
MYCN (N-Myc Proto-Oncogene Protein (MYCN))

适用

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宿主

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小鼠

克隆类型

  • 48
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单克隆

标记

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This MYCN antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

PCRP-MYCN-1A9
  • 抗原表位

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    AA 335-463

    原理

    MYCN Antibody

    特异性

    The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant protein domain (around aa335-463) of human MYCN protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    MYCN (N-Myc Proto-Oncogene Protein (MYCN))

    别名

    MYCN

    背景

    Class E basic helix-loop-helix protein 37 (bHLHe37), MODED, N-myc proto-oncogene protein, Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene, ODED, pp65/67, v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived

    293T whole cell lysates or recombinant Human n-Myc protein.

    分子量

    49.56 kDa

    基因ID

    4613, 25960

    UniProt

    P04198
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