我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

TYR 抗体 (AA 332-474)

The 小鼠单克隆 anti-TYR antibody is suitable to detect TYR in samples from 人. It has been validated for IHC, IF 和 FACS.

产品编号 ABIN7863484

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TYR 抗体 (AA 332-474) (ABIN7863484)

抗原

See all TYR 抗体

TYR (Tyrosinase (TYR))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This TYR antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

TYR-3829

Discover our top product TYR Primary Antibody

抗原表位
15

7

5

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 332-474

原理

Tyrosinase (Melanoma Marker) Antibody

特异性

Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.

纯化方法

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

免疫原

Recombinant fragment (around aa332-474) of human Tyrosinase protein (exact sequence is proprietary)

亚型

IgG1, kappa
anti-Tyrosinase (TYR) (AA 1-377) antibody
TYR 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A2-F4 unconjugated

anti-Tyrosinase (TYR) (AA 20-340) antibody
TYR 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated

anti-Tyrosinase (TYR) (AA 486-513) antibody
TYR 适用: 人 IHC, WB, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Tyrosinase (TYR) (AA 1-377) antibody
TYR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Tyrosinase (TYR) antibody
TYR 适用: 人, 小鼠, 猴 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosinase (TYR) (AA 486-513), (C-Term) antibody
TYR 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19155 unconjugated

anti-Tyrosinase (TYR) (C-Term) antibody
TYR 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosinase (TYR) antibody
TYR 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal T311 unconjugated

anti-Tyrosinase (TYR) (AA 176-205) antibody
TYR 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19154 unconjugated

anti-Tyrosinase (TYR) (C-Term) antibody
TYR 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

TYR (Tyrosinase (TYR))

别名

Tyrosinase

背景

ATN, CMM8, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, Oculocutaneous albinism IA, SHEP3, SK29-AB, Tumor rejection antigen AB, TYR
SK-MEL-13, SK-MEL-19, SK-MEL-30 or SK-MEL-37 cells. Human skin or melanoma.

分子量

70-80kDa

基因ID

7299, 503555

UniProt

P14679