ENPP3 抗体 (AA 300-600)
Our Local Distributor
北京 101111
Quick Overview for ENPP3 抗体 (AA 300-600) (ABIN7859856)
抗原
See all ENPP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 300-600
-
原理
- CD203c / ENPP3 (Basophil Marker) Antibody
-
特异性
- Ecto-nucleotide pyrophosphatase/phosphodiesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3, also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. Hovever, these allergies are not the only condition associated with CD203c upregulation, CD203c upregulation may also serve as a tumor marker for colon carcinoma.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment (around aa300-600) of human ENPP3 protein (exact sequence is proprietary)
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
-
别名
- CD203c
-
背景
- B10, NPP3, PDNP3, CD203c, PD-IBETA
-
分子量
- 100kDa
-
基因ID
- 5169
-
UniProt
- O14638
-
途径
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
抗原
-