RBP4 抗体 (AA 29-148)
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Quick Overview for RBP4 抗体 (AA 29-148) (ABIN7863339)
抗原
See all RBP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-148
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原理
- RBP4 / Retinol Binding Protein 4 Antibody
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特异性
- Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa29-148) of human RBP4 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 63-245) antibody
RBP4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 18-201) antibodyRBP4 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-202) antibodyRBP4 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-202) antibodyRBP4 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D9 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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别名
- RBP4
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背景
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Plasma retinol binding protein 4 (PRBP), RDCCAS, Retinol binding protein 4 interstitial
HeP-G2 cells. Human kidney, pancreas or liver tissues.
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分子量
- 25kDa
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基因ID
- 5950, 50223
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UniProt
- P02753
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途径
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
抗原
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