CDH6 抗体 (AA 250-450)
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Quick Overview for CDH6 抗体 (AA 250-450) (ABIN7865425)
抗原
See all CDH6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 250-450
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原理
- Cadherin-6 (CDH6) / K-Cadherin Antibody
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特异性
- This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 250-450) of human Cadherin 6 protein (CDH6) (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-K-Cadherin (CDH6) (AA 281-380) antibody
CDH6 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-K-Cadherin (CDH6) antibodyCDH6 适用: 人, 大鼠 WB, IHC, IHC (fro), ICC 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-K-Cadherin (CDH6) (AA 513-612) antibodyCDH6 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-K-Cadherin (CDH6) antibodyCDH6 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-K-Cadherin (CDH6) antibodyCDH6 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB5060 unconjugated Recombinant Antibody
anti-K-Cadherin (CDH6) (AA 1-250) antibodyCDH6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-K-Cadherin (CDH6) antibodyCDH6 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-K-Cadherin (CDH6) (AA 665-695), (C-Term) antibodyCDH6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-K-Cadherin (CDH6) (AA 1-663) antibodyCDH6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-K-Cadherin (CDH6) (C-Term) antibodyCDH6 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CDH6 (K-Cadherin (CDH6))
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别名
- Cadherin-6
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背景
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Cadherin-6, CDH6, CAD6, KCAD,
Human kidney or renal cell carcinoma.
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分子量
- 130kDa
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基因ID
- 1004, 124776
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UniProt
- P55285
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途径
- Cell-Cell Junction Organization
抗原
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