Recombinant ATRX 抗体 (AA 2200-2450)
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Quick Overview for Recombinant ATRX 抗体 (AA 2200-2450) (ABIN7863264)
抗原
See all ATRX 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2200-2450
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原理
- Recombinant ATRX / RAD54 (Alpha Thalassemia Mental Retardation) Antibody
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特异性
- ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 °™ to mediate chromosomal segregation. Mutations in the ATRX gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with °™ thalassemia or ATRX syndrome
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa2200-2450) of human ATRX protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-helicase 2, X-linked (ATRX) (C-Term) antibody
ATRX 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2161-2443) antibodyATRX 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2492) antibodyATRX 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8B2H9 unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2410) antibodyATRX 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-helicase 2, X-linked (ATRX) (N-Term) antibodyATRX 适用: 人, 小鼠 IHC, ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC 宿主: 兔 Monoclonal ATRX-2900R unconjugated Recombinant Antibody
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC 宿主: 小鼠 Monoclonal 39f unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 634-663), (C-Term) antibodyATRX 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB20635 unconjugated
anti-helicase 2, X-linked (ATRX) (C-Term) antibodyATRX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ATRX (helicase 2, X-linked (ATRX))
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别名
- ATRX
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背景
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Alpha thalassemia/mental retardation syndrome X linked homolog, ATP-dependent helicase ATRX, ATR2, ATRX, DNA-dependent ATPase and helicase, MRXHF1, RAD54, RAD54L, SFM1, SHS, Transcriptional regulator ATRX, X-linked helicase II, X-linked nuclear protein, XH2, XNP, Znf-HX
adrenal, HeLa or A431 cells. Human pancreas, Kidney, ovary, prostate or stomach., Raji
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分子量
- 280kDa
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基因ID
- 546, 533526, 653797
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UniProt
- P46100
抗原
-
