DBH 抗体 (AA 200-400)
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北京 101111
Quick Overview for DBH 抗体 (AA 200-400) (ABIN7859471)
抗原
See all DBH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-400
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原理
- DBH / Dopamine Beta-Hydroxylase Antibody
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特异性
- Dopamine ≤-hydroxylase (DBH) catalyzes the conversion of dopamine to noradrenaline in the biosynthesis of catecholamines. DBH is selectively expressed in noradrenergic and adrenergic neurons, as well as in neuroendocrine cells, and it serves as a specific protein marker for noradrenergic processes. The active form of DBH is a homotetramer, which is found in the lumen of synaptic vesicles of corresponding nerve cells, where it localizes to both the membrane and cytosol. DBH is induced by nerve growth factor and Insulin growth factor-1 and is regulated by intracellular second messengers protein kinase A, cyclic AMP, diacyl glycerol and Ca2+. Expression of DBH is transcriptionally mediated by Sp1, CREB and AP-1 proteins including c-Fos, c-Jun and JunD.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-400) of human DBH protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 27-56) antibody
DBH 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 34-64), (N-Term) antibodyDBH 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 335-571) antibodyDBH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 27-56), (N-Term) antibodyDBH 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal RB19267 unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 437-448) antibodyVerified DBH 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (Internal Region) antibodyDBH 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (N-Term) antibodyDBH 适用: 人, 灵长类 WB, IHC, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (C-Term) antibodyDBH 适用: 人, 小鼠, 灵长类 WB, IHC, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 150-250) antibodyDBH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (AA 270-303) antibodyDBH 适用: 人 WB 宿主: 兔 Polyclonal RB48156 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))
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别名
- DBH
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背景
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dbh, DBM, Dopamine beta hydroxylase, Dopamine beta monooxygenase, Dopamine beta-hydroxylase (dopamine beta-monooxygenase), Soluble dopamine beta-hydroxylase
Human adrenal gland or adrenal pheochromocytoma.
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分子量
- 78/84 kDa
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基因ID
- 1621, 591890
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UniProt
- P09172
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途径
- Carbohydrate Homeostasis
抗原
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