BTBD9 抗体 (AA 200-400)
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北京 101111
Quick Overview for BTBD9 抗体 (AA 200-400) (ABIN7864599)
抗原
See all BTBD9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-400
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原理
- BTBD9 Antibody
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特异性
- BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6), a condition characterized by an uncontrollable urge to move the legs while resting.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-400) of human BTBD9 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-BTB (POZ) Domain Containing 9 (BTBD9) (AA 2-70) antibody
BTBD9 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-BTB (POZ) Domain Containing 9 (BTBD9) (AA 237-262) antibodyBTBD9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21696 unconjugated
anti-BTB (POZ) Domain Containing 9 (BTBD9) (AA 1-582) antibodyBTBD9 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 9 (BTBD9) (AA 2-70) antibodyBTBD9 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 9 (BTBD9) (AA 1-582) antibodyBTBD9 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 9 (BTBD9) (AA 237-262) antibodyBTBD9 适用: 人, 小鼠 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 9 (BTBD9) antibodyBTBD9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))
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别名
- BTBD9
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背景
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BTB/POZ domain-containing protein 9
Human fallopian tube|lung or lymph node.
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分子量
- 69kDa
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基因ID
- 114781, 603858
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UniProt
- Q96Q07
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途径
- Transition Metal Ion Homeostasis
抗原
-
