TGF-beta 抗体 (AA 200-390)
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Quick Overview for TGF-beta 抗体 (AA 200-390) (ABIN7863863)
抗原
See all TGF-beta (TGFb) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-390
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原理
- TGF-beta (Transforming Growth Factor beta) Antibody
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特异性
- This MAb recognizes TGF beta 1, 2 and 3. Three TGF≤s have been identified in mammals. TGF≤1, TGF≤2 and TGF≤3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF≤ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF≤3 protein has approximately 80 % identity to the mature region of both TGF≤1 and TGF≤2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGF≤ s inhibits the growth of epithelial cells and stimulate the growth of mesenchymal cells. 79oΩ
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-390) of human TGFB protein
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亚型
- IgG2, kappa
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anti-TGF-beta (TGFb) (AA 301-350) antibody
TGFb 适用: 人, 小鼠, 大鼠, 兔, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人, 小鼠, 大鼠, 兔, 哺乳动物 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊, Mink, Mustelid WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal TB21 unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人, 小鼠, 大鼠, Cow, 犬, Hamster, 猴 ELISA, Func 宿主: 小鼠 Monoclonal TGFB-510 unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人 ELISA, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal TB21 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- TGF-beta (TGFb)
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别名
- TGF-beta
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背景
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ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), TGF beta2 (TGFB2), TGF beta3 (TGFB3), TGFbeta (TGFB)
Salivary gland carcinoma
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分子量
- 13kDa
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基因ID
- 7040, 645227
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UniProt
- P01137
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途径
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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