Galectin 9 抗体 (AA 200-355)
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Quick Overview for Galectin 9 抗体 (AA 200-355) (ABIN7859445)
抗原
See all Galectin 9 (LGALS9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-355
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原理
- Galectin-9 (LGALS9) (Marker of T-Cell Exhaustion) Antibody
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特异性
- Galectins are a family of soluble ≤-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-9, also known as Ecalectin, Gal-9, hUAT2, HOM-HD-21 or LGALS9, maps to human chromosome 17 and encodes a 36 kDa protein. Galectin-9 is an integral membrane protein that exists as two isoforms, a long form and a short form, which differ by an internal stretch of 32 amino acids. Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes that is expressed in organs of the gastrointestinal tract, aorta, liver, kidney, liver, pancreatic islets, lung, tonsil and some colorectal carcinoma, and in the cell lines HUVEC, U-937, HL60, HeLa and Jurkat. Introduction of IL-1beta enhances Galectin-9 expression. Increased expression of Galectin-9 induces apoptosis in thymocytes and CD8+ cells. Galectin-9 is involved in immuno/inflammation processes in potential-sensitive uric acid translocation and contributes to inflammatory reactions in the central nervous system (CNS).
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-355) of human LGALS9 protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
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别名
- Galectin-9
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背景
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Gal-9 | LGALS9
Human lung, liver, breast or kidney.
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分子量
- 36kDa
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基因ID
- 3965
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UniProt
- O00182
抗原
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