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Galectin 9 抗体 (AA 200-355)

The 小鼠 单克隆 anti-Galectin 9 antibody is suitable to detect Galectin 9 in samples from 人. It has been validated for IHC.
产品编号 ABIN7859445
发货至: 中国
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Quick Overview for Galectin 9 抗体 (AA 200-355) (ABIN7859445)

抗原

See all Galectin 9 (LGALS9) 抗体
Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

适用

  • 72
  • 45
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  • 2
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  • 1
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宿主

  • 89
  • 14
  • 2
  • 1
小鼠

克隆类型

  • 83
  • 17
  • 4
单克隆

标记

  • 56
  • 17
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  • 1
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This Galectin 9 antibody is un-conjugated

应用范围

  • 79
  • 40
  • 32
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  • 18
  • 15
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  • 6
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Immunohistochemistry (IHC)

克隆位点

LGALS9-7689
  • 抗原表位

    • 16
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
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    AA 200-355

    原理

    Galectin-9 (LGALS9) (Marker of T-Cell Exhaustion) Antibody

    特异性

    Galectins are a family of soluble ≤-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-9, also known as Ecalectin, Gal-9, hUAT2, HOM-HD-21 or LGALS9, maps to human chromosome 17 and encodes a 36 kDa protein. Galectin-9 is an integral membrane protein that exists as two isoforms, a long form and a short form, which differ by an internal stretch of 32 amino acids. Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes that is expressed in organs of the gastrointestinal tract, aorta, liver, kidney, liver, pancreatic islets, lung, tonsil and some colorectal carcinoma, and in the cell lines HUVEC, U-937, HL60, HeLa and Jurkat. Introduction of IL-1beta enhances Galectin-9 expression. Increased expression of Galectin-9 induces apoptosis in thymocytes and CD8+ cells. Galectin-9 is involved in immuno/inflammation processes in potential-sensitive uric acid translocation and contributes to inflammatory reactions in the central nervous system (CNS).

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa200-355) of human LGALS9 protein (exact sequence is proprietary)

    亚型

    IgG2, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

    别名

    Galectin-9

    背景

    Gal-9 | LGALS9

    Human lung, liver, breast or kidney.

    分子量

    36kDa

    基因ID

    3965

    UniProt

    O00182
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