AMBP 抗体 (AA 200-353)
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北京 101111
Quick Overview for AMBP 抗体 (AA 200-353) (ABIN7864718)
抗原
See all AMBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-353
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原理
- AMBP (Alpha 1 Microglobulin) / Bikunin Antibody
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特异性
- The AMBP (±-1-Microglobulin/Bikunin precursor) gene encodes a protein precursor, known as AMBP, that is cleaved to produce two distinct proteins, designated ±-1-Microglobulin and Bikunin. ±-1-Microglobulin, also known as protein HC, is a member of the lipocalin superfamily and is secreted mainly in plasma, urine and cerebrospinal fluid. Thought to have reductase/dehydrogenase activity, ±-1-Microglobulin exhibits immunosuppressive properties, such as cytokine secretion and inhibition of antigen-induced lymphocyte cell proliferation, and may be involved in the reduction of biological pro-oxidants. The second protein cleavage product, designated Bikunin and also known as inter-±-trypsin inhibitor light chain, ITI-LC or urinary trypsin inhibitor, is a widely expressed protein that is stored in the granules of human connective tissue mast cells. One of many proteins in the Kunitz-type protease inhibitor family, Bikunin prevents autodigestion by exocrine enzymes, such as trypsinogen and chymo-trypsinogen, and plays a role in the antiinflammatory/antiproteinase immune response. Unlike ±-1-Microglobulin, Bikunin is implicated in the pathogenesis of a number of renal diseases, such as urolithiasis.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-353) of human AMBP protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-alpha 1 Microglobulin/bikunin precursor (AMBP) (AA 19-352) antibody
AMBP 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) (AA 1-352) antibodyAMBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) (AA 22-203) antibodyAMBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) (AA 18-202) antibodyAMBP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) antibodyKD Validated AMBP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3200 unconjugated Recombinant Antibody
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) antibodyAMBP 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) (AA 77-104) antibodyAMBP 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) (C-Term) antibodyAMBP 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) antibodyAMBP 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-alpha 1 Microglobulin/bikunin precursor (AMBP) antibodyAMBP 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F2 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))
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别名
- AMBP
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背景
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A1M, Alpha 1 microglobulin/bikunin precursor, Alpha 1 microglycoprotein, Bikunin, Complex-forming glycoprotein heterogeneous in charge, EDC1, Growth inhibiting protein 19, HCP, HI30, IATIL, ITI, ITI-LC, ITIL, Microglobulin (alpha 1), Protein AMBP, Protein HC, Trypstatin, Uristatin, Uronic-acid-rich protein, UTI
Human liver or placenta.
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分子量
- 30kDa
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基因ID
- 259, 436911
抗原
-
