Recombinant Syndecan 1 抗体 (AA 200-300)
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北京 101111
Quick Overview for Recombinant Syndecan 1 抗体 (AA 200-300) (ABIN7863378)
抗原
See all Syndecan 1 (SDC1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-300
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原理
- Recombinant CD138 / Syndecan-1 (SDC1) (Plasma Cell Marker) Antibody
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特异性
- CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 ispredominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma. In the following, the large majority of cases is CD138 positive: skin squamous cell carcinoma and basal cell carcinoma, colorectal adenocarcinoma, cholangiocarcinoma, transitional cell carcinoma, endometrial adenocarcinoma, ductal and lobular breast carcinoma, hepatocellular carcinoma, renal cell carcinoma, and lung adenocarcinoma.CD138 is a very sensitive and specific marker for identification of plasma cells and plasma cell differentiation within haematolymphoid tissues in benign and neoplastic conditions.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-300) of human CD138 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Syndecan 1 (SDC1) (AA 28-171) antibody
SDC1 适用: 人, 小鼠 WB, IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1A3H4 unconjugated
anti-Syndecan 1 (SDC1) (AA 210-238), (C-Term) antibodySDC1 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 587CT7-3-6-5 unconjugated
anti-Syndecan 1 (SDC1) (AA 23-251) antibodySDC1 适用: 人, 小鼠 IHC, FACS, ICC 宿主: 兔 Monoclonal BLR323M unconjugated Recombinant Antibody
anti-Syndecan 1 (SDC1) (AA 58-313) antibodySDC1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 23-253) antibodySDC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 23-251) antibodySDC1 适用: 人, 小鼠 IHC, FACS, ICC 宿主: 兔 Monoclonal BLR323M unconjugated Recombinant Antibody
anti-Syndecan 1 (SDC1) (AA 201-310) antibodySDC1 适用: 人, 大鼠, 小鼠, Cow WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 23-251) antibodySDC1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR324M unconjugated Recombinant Antibody
anti-Syndecan 1 (SDC1) (C-Term) antibodySDC1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 1 (SDC1) (AA 23-251) antibodySDC1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR324M unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Syndecan 1 (SDC1)
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别名
- CD138
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背景
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Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor, SDC1, SYND1, Syndecan Proteoglycan 1, Syndecan-1
Human tonsil or lymph node.
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分子量
- 85kDa
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基因ID
- 6382, 224607
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UniProt
- P18827
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
抗原
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