STING1 (AA 190-290) 抗体
The 小鼠 单克隆 anti-STING1 antibody (Clone STING1-7431) (ABIN7862969) specifically detects STING1 in IHC.
The antibody is reactive with 人 samples.
产品编号 ABIN7862969
发货至:
中国
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中国
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北京 101111
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Quick Overview for STING1 (AA 190-290) 抗体 (ABIN7862969)
抗原
STING1
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC)
克隆位点
STING1-7431
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抗原表位
- AA 190-290
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原理
- STING1 / TMEM173 Antibody
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特异性
- TMEM17 (transmembrane protein 173) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa190-290) of human TMEM173 protein (exact sequence is proprietary)
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亚型
- IgG
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anti-STING1 (AA 190-290) antibody
适用: 人 IHC 宿主: 小鼠 Monoclonal 515M unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- STING1
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背景
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Endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, Mediator of IRF3 activation, MITA, NET23, MPYS, Mitochondrial mediator of IRF3 activation, N terminal methionine proline tyrosine serine plasma membrane tetraspanner, Stimulator of interferon genes protein, Transmembrane protein 173
Cytoplasmic expression in several tissues including cells in respiratory tract, fallopian tube and cells in lymphoid tissues.
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分子量
- 37-50kDa
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基因ID
- 340061, 379754
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UniProt
- Q86WV6
抗原
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