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Paired Box 3 抗体 (AA 150-350)

The 小鼠 单克隆 anti-Paired Box 3 antibody (Clone PAX3-8426) (ABIN7859227) specifically detects Paired Box 3 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7859227
发货至: 中国
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Quick Overview for Paired Box 3 抗体 (AA 150-350) (ABIN7859227)

抗原

See all Paired Box 3 (PAX3) 抗体
Paired Box 3 (PAX3)

适用

  • 65
  • 26
  • 21
  • 8
  • 7
  • 7
  • 7
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 46
  • 16
  • 3
小鼠

克隆类型

  • 50
  • 15
单克隆

标记

  • 46
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Paired Box 3 antibody is un-conjugated

应用范围

  • 42
  • 34
  • 10
  • 7
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)

克隆位点

PAX3-8426
  • 抗原表位

    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-350

    原理

    PAX3 Antibody

    特异性

    Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa150-350) of human PAX3 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Paired Box 3 (PAX3)

    别名

    PAX3

    背景

    CDHS, HUP2, Paired box 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired domain gene HuP2, PAX3/FKHR fusion gene, Sp, splotch, Waardenburg syndrome 1, WS1, WS3

    Human skin and skeletal muscle tissue.

    分子量

    56kDa

    基因ID

    5077, 42146

    UniProt

    P23760

    途径

    Sensory Perception of Sound, Tube Formation
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