GBX2 抗体 (AA 150-350)
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Quick Overview for GBX2 抗体 (AA 150-350) (ABIN7859213)
抗原
See all GBX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-350
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原理
- GBX2 / Gastrulation Brain Homeobox 2 Antibody
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特异性
- The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes GBX2 and OTX2. GBX2 and OTX2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, GBX2 negatively regulates OTX2 expression along the anterior-posterior axis, GBX2- mutants demonstrate an expanded OTX2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. GBX2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is overexpressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of GBX2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that GBX2 expression may be required for growth of malignant prostate cells.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa150-350) of human GBX2 protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-Gastrulation Brain Homeo Box 2 (GBX2) (Internal Region) antibody
Verified GBX2 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 114-182) antibodyGBX2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 114-182) antibodyGBX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 65-248) antibodyGBX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 181-230) antibodyGBX2 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 141-230) antibodyGBX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 114-182) antibodyGBX2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 103-131) antibodyGBX2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 1-250) antibodyGBX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 179-228) antibodyGBX2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- GBX2 (Gastrulation Brain Homeo Box 2 (GBX2))
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别名
- GBX2
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背景
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Gastrulation and brain-specific homeobox protein 2, Gastrulation brain homeobox 2, Homeobox protein GBX2, Homeobox protein STRA7, Mmoxa
Human placenta or brain.
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分子量
- 37kDa
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基因ID
- 2637, 184945
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途径
- Dopaminergic Neurogenesis
抗原
-
