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Recombinant GATA3 抗体 (AA 150-250)

This 兔 单克隆 antibody specifically detects GATA3 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7859141
发货至: 中国
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Quick Overview for Recombinant GATA3 抗体 (AA 150-250) (ABIN7859141)

抗原

See all GATA3 抗体
GATA3 (GATA Binding Protein 3 (GATA3))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This GATA3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

GATA3-7685R
  • 抗原表位

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    AA 150-250

    原理

    Recombinant GATA-3 (Breast and Urothelial Marker) Antibody

    特异性

    GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50 kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67 % of urothelial Carcinomas, but none of prostate or renal carcinomas.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa150-250) of human GATA-3 protein (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    GATA3 (GATA Binding Protein 3 (GATA3))

    别名

    GATA-3

    背景

    GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3

    Human breast or urothelial carcinoma tissue.

    分子量

    50kDa

    基因ID

    2625, 524134

    UniProt

    P23771

    途径

    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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