BCOR 抗体 (AA 100-400)
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北京 101111
Quick Overview for BCOR 抗体 (AA 100-400) (ABIN7864482)
抗原
See all BCOR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-400
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原理
- BCOR Antibody
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特异性
- Bcl-6, a transcriptional repressor, can promote or inhibit apoptosis depending on the cell type and also plays an important role in normal immune responses. Bcl-6 negatively regulates NFé 79oΩB expression, thereby inhibiting NFé 79oΩB-mediated cellular functions and is frequently found to be deregulated in non-Hodgkin s lymphoma. BCoR (Bcl-6 corepressor) is a 1,755 amino acid protein that associates with histone deacetylases (HDACs) to transcriptionally repress Bcl-6. With ubiquitous expression, BCoR is localized to the nucleus where it interacts with other proteins through its three ANK repeat domains. Mutations in the gene encoding BCoR result in microphthalmia with associated anomalies 2, also known as anophthalmia, which is characterized by variable features, such as renal aplasia, mental retardation, hyospadias, microencephaly and cryptorchidism. There are four isoforms of BCoR which are produced as a result of alternative splicing events.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 100-400) of human BCOR protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-BCL6 Co-Repressor (BCOR) (AA 1107-1137) antibody
BCOR 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19040 unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1361-1460) antibodyBCOR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (Internal Region) antibodyBCOR 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (N-Term) antibodyVerified BCOR 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1-1004) antibodyBCOR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1553-1755) antibodyBCOR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 25-75) antibodyBCOR 适用: 人 IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (Internal Region) antibodyBCOR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (Internal Region) antibodyBCOR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1705-1755) antibodyBCOR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- BCOR (BCL6 Co-Repressor (BCOR))
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别名
- BCOR
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背景
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ANOP2, BCL 6 interacting corepressor, BCL6 interacting corepressor, BCoR, KIAA1575, MAA2, MCOPS2
Ubiquitously expression.
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分子量
- 192kDa
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基因ID
- 54880, 659681
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UniProt
- Q6W2J9
抗原
-
