Luteinizing Hormone 抗体 (AA 100-300)
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Quick Overview for Luteinizing Hormone 抗体 (AA 100-300) (ABIN7859022)
抗原
See all Luteinizing Hormone (LH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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原理
- Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody
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特异性
- Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 100-300) of human LHCGR protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Luteinizing Hormone (LH) (AA 25-120) antibody
LH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone (LH) antibodyLH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone (LH) antibodyLH 适用: 人, 大鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone (LH) antibodyLH 适用: 人, 大鼠, 犬 ELISA 宿主: 小鼠 Monoclonal 157-10H10 unconjugated
anti-Luteinizing Hormone (LH) antibodyLH 适用: 人, 大鼠, 犬 ELISA 宿主: 小鼠 Monoclonal 156-10B7 unconjugated
anti-Luteinizing Hormone (LH) antibodyLH 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Luteinizing Hormone (LH)
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别名
- Luteinizing Hormone
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物质类
- Hormone
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背景
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Gonadotropin receptor, GTHR-II, HHG, LCGR, LGR2, LH-R, LH/CG-R, LH/CGR, LHCGR, LHR, LHRHR, LSH-R, Luteinizing hormone receptor, Luteinizing hormone/choriogonadotropin receptor, Lutropin choriogonadotropic receptor, Lutropin-choriogonadotropic hormone receptor, ULG5
HepG2 or Jurkat cells. Human ovarian carcinoma.
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分子量
- 78-85kDa
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基因ID
- 3973, 468490
抗原
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