CPA1 抗体 (AA 100-300)
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北京 101111
Quick Overview for CPA1 抗体 (AA 100-300) (ABIN7858993)
抗原
See all CPA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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原理
- Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker) Antibody
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特异性
- Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa100-300) of human CPA1 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))
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别名
- Carboxypeptidase A1
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背景
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Carboxypeptidase A1 (pancreatic), CPA1, Pancreatic Carboxypeptidase A1, Procarboxypeptidase A1 pancreatic
Pancreas.
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分子量
- 47kDa
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基因ID
- 1357, 2879
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UniProt
- P15085
抗原
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