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S100P 抗体 (AA 1-95)

The 小鼠 单克隆 anti-S100P antibody (Clone S100P-7374) (ABIN7864121) specifically detects S100P in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7864121
发货至: 中国
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Quick Overview for S100P 抗体 (AA 1-95) (ABIN7864121)

抗原

See all S100P 抗体
S100P (S100 Calcium Binding Protein P (S100P))

适用

  • 95
  • 2
  • 2

宿主

  • 68
  • 27
小鼠

克隆类型

  • 58
  • 37
单克隆

标记

  • 61
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
This S100P antibody is un-conjugated

应用范围

  • 46
  • 43
  • 22
  • 20
  • 17
  • 13
  • 13
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)

克隆位点

S100P-7374
  • 抗原表位

    • 29
    • 11
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-95

    原理

    S100P / MIG9 Antibody

    特异性

    S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-95) of human MIG9 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    S100P (S100 Calcium Binding Protein P (S100P))

    别名

    S100P

    背景

    Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P

    Human pancreatic adenocarcinoma|placenta or spleen tissue.

    分子量

    10kDa

    基因ID

    6286, 2962

    UniProt

    P25815

    途径

    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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