KCNIP2 抗体 (AA 1-270)
Our Local Distributor
北京 101111
Quick Overview for KCNIP2 抗体 (AA 1-270) (ABIN7864996)
抗原
See all KCNIP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-270
-
原理
- KCNIP2 / KCHIP2 Antibody
-
特异性
- In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4±-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain, KChIP2 expressed in heart, brain, and lung, and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain, KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99 % nucleotide homology to DREAM, suggesting that KChIPs may have activity beyond modulation of Kv4 channels.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment (around aa1-270) of human KCNIP2 protein (exact sequence is proprietary)
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))
-
别名
- KCNIP2
-
背景
-
A type potassium channel modulatory protein 2, Cardiac voltage gated potassium channel modulatory subunit, DKFZp566L1246, KChIP2, Kcnip2, Kv channel interacting protein 2, Potassium channel interacting protein 2
Human brain.
-
分子量
- 27-36kDa
-
基因ID
- 30819, 97044
-
UniProt
- Q9NS61
抗原
-