HMMR 抗体 (AA 1-250)
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北京 101111
Quick Overview for HMMR 抗体 (AA 1-250) (ABIN7865052)
抗原
See all HMMR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-250
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原理
- CD168 / RHAMM Antibody
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特异性
- Hyaluronic acid (HA) is a nonsulfated glycosaminoglycan that regulates cell adhesion and migration. HA effects are mediated through two receptors, CD44 (also designated HCAM) and the receptor of hyaluronic acid mediated motility (RHAMM). RHAMM, also designated intracellular hyaluronic acid binding protein (IHABP) and CD168, is a matrix receptor, which is linked to the plasma membrane by a GPI anchor and regulates cell motility. RHAMM expression is upregulated in malignant lymphoid tissues and is subsequently implicated in tumor progression and metastasis formation, as well as signal transduction. Although still unclear, RHAMM is thought to exist as several isoforms ranging in size. A variant isoform, designated v4, is a protein that when over-expressed, is thought to be the cause of transformation and metastasis formation in fibroblasts.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-250) of human HMMR protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 341-440) antibody
HMMR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 306-497) antibodyHMMR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F2C9 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 668-697), (C-Term) antibodyHMMR 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17647 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 51-150) antibodyHMMR 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 577-724) antibodyHMMR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyHMMR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 1-300) antibodyHMMR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyKD Validated HMMR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB13600 unconjugated Recombinant Antibody
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyHMMR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 478-653) antibodyHMMR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
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别名
- CD168
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背景
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CD168, CD168 antigen, HMMR, Hyaluronan-mediated motility receptor (RHAMM), IHABP, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility
breast cancer or placenta.|Human breast
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分子量
- 85-90kDa
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基因ID
- 3161, 728200
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UniProt
- O75330
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途径
- Glycosaminoglycan Metabolic Process
抗原
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