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PAX4 抗体 (AA 1-200)

The 小鼠 单克隆 anti-PAX4 antibody is suitable to detect PAX4 in samples from 人. It has been validated for IHC.
产品编号 ABIN7858644
发货至: 中国
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Quick Overview for PAX4 抗体 (AA 1-200) (ABIN7858644)

抗原

See all PAX4 抗体
PAX4 (Paired Box 4 (PAX4))

适用

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宿主

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小鼠

克隆类型

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  • 11
单克隆

标记

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This PAX4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

PAX4-7599
  • 抗原表位

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    AA 1-200

    原理

    PAX4 Antibody

    特异性

    Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing ≤ cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ≤ cell lines MIN6, ≤ TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-200) of human PAX4 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    PAX4 (Paired Box 4 (PAX4))

    别名

    PAX4

    背景

    KPD, MODY9, Paired box 4

    DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen

    分子量

    38kDa

    基因ID

    5078, 129706

    UniProt

    O43316
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