PAX4 抗体 (AA 1-200)
Our Local Distributor
北京 101111
Quick Overview for PAX4 抗体 (AA 1-200) (ABIN7858642)
抗原
See all PAX4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-200
-
原理
- PAX4 Antibody
-
特异性
- Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing ≤ cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ≤ cell lines MIN6, ≤ TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment (around aa1-200) of human PAX4 protein (exact sequence is proprietary)
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- PAX4 (Paired Box 4 (PAX4))
-
别名
- PAX4
-
背景
-
KPD, MODY9, Paired box 4
DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen
-
分子量
- 38kDa
-
基因ID
- 5078, 129706
-
UniProt
- O43316
抗原
-