IL22RA2 抗体 (AA 1-200)
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北京 101111
Quick Overview for IL22RA2 抗体 (AA 1-200) (ABIN7864435)
抗原
See all IL22RA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- IL22RA2 Antibody
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特异性
- IL-22R±2 (Interleukin-22 receptor ±2 chain), also known as IL-22 binding protein (IL-22BP), cytokine receptor family class II member 10 (CRF2-10) or CRF2- soluble 1 (CRF2-S1), is a soluble, nonsignaling single chain receptor for IL-22. It is highly expressed in intestine and lymph nodes and is also found in spleen, kidney and liver. IL-22R±2 has a cytokine-binding domain that contains two FnIII domains. Its affinity for IL-22 is 4- to 10-fold higher than that of the membrane-bound IL-22 receptor, however it has a dissociation rate up to 20 times lower. By binding to IL-22, IL-22R±2 prevents the binding to the IL-22 membrane-bound receptor and therefore inhibits IL-22 signaling. This suggests that IL-22R±2 may be important in regulating inflammatory responses. In addition, IL-22R±2 can be induced by lipopolysaccharides (LPSs).
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-200) of human IL22RA2 protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 31-223) antibody
IL22RA2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 30-228) antibodyIL22RA2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 165-263) antibodyIL22RA2 适用: 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-231) antibodyIL22RA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-263) antibodyIL22RA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) antibodyIL22RA2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (Internal Region) antibodyIL22RA2 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) antibodyIL22RA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 15-42), (N-Term) antibodyIL22RA2 适用: 人 WB 宿主: 兔 Polyclonal RB38824 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))
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别名
- IL22RA2
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背景
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IL 22BP, IL22RA2, Class II cytokine receptor, CRF2-10, CRF2-S1, CRF2X, Cytokine receptor class-II member 10, Cytokine receptor family type 2 soluble 1, IL-22 receptor subunit alpha-2, IL-22BP, IL-22R-alpha-2, Interleukin 22 binding protein, Interleukin 22 Receptor alpha 2, Class II cytokine receptor
carcinoma or liver.|colon|Human tonsil
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分子量
- 27 kDa
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基因ID
- 116379, 126891
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UniProt
- Q969J5
抗原
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