IL20RA 抗体 (AA 1-200)
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北京 101111
Quick Overview for IL20RA 抗体 (AA 1-200) (ABIN7858558)
抗原
See all IL20RA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- IL20RA (Interleukin 20 Receptor Subunit Alpha) Antibody
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特异性
- The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-l. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ra and IL-20Rb. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ra and IL-20Rb all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-200) of human IL20RA protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-Interleukin 20 Receptor alpha (IL20RA) (AA 135-171) antibody
IL20RA 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) antibodyIL20RA 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) (AA 30-250) antibodyIL20RA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) (AA 159-175) antibodyIL20RA 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) (C-Term) antibodyIL20RA 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) (AA 268-538) antibodyIL20RA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) (AA 273-543) antibodyIL20RA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 Receptor alpha (IL20RA) (AA 269-545) antibodyIL20RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- IL20RA (Interleukin 20 Receptor alpha (IL20RA))
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别名
- IL20RA
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背景
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class II cytokine receptor ZCYTOR7, CRF2 8, Cytokine receptor class II member 8, Cytokine receptor family 2 member 8, IL 20R1, IL-20 receptor subunit alpha, IL-20R1, IL20 Receptor alpha, Interleukin 20 receptor alpha chain,
brain or psoriatic skin.|Human skin|testis
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分子量
- 90-100kDa
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基因ID
- 53832, 445868
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UniProt
- Q9UHF4
抗原
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