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IL18R1 抗体 (AA 1-200)

The 小鼠 单克隆 anti-IL18R1 antibody is suitable to detect IL18R1 in samples from 人. It has been validated for IHC.
产品编号 ABIN7864578
发货至: 中国
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Quick Overview for IL18R1 抗体 (AA 1-200) (ABIN7864578)

抗原

See all IL18R1 抗体
IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL18R1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

IL18R1-7591
  • 抗原表位

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    AA 1-200

    原理

    IL18R1 Antibody

    特异性

    Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-é 79oΩ production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1± or IL-1≤. The association of IL-18 to IL-18R leads to activation of NFé 79oΩB. At present two subunits of IL-18R have been characterized: IL-18R± and IL-18R≤. IL-18R± has been described as the ligand-binding chain and IL-18R≤ as the signal-transduction chain.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-200) of human IL18R1 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

    别名

    IL18R1

    背景

    CD218 antigen-like family member A, CDw218a antigen, IL-18R1, IL-1Rrp, IL1 receptor-related protein, Il18ralpha,IL1R-rp, IL1RRP, Interleukin 18 receptor, alpha chain

    Human lung|leukocytes|liver or thymus.|spleen

    分子量

    62kDa

    基因ID

    8809, 469521

    UniProt

    Q13478
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