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HSD17B13 抗体 (AA 1-200)

This 小鼠 单克隆 antibody specifically detects HSD17B13 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7865381
发货至: 中国
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Quick Overview for HSD17B13 抗体 (AA 1-200) (ABIN7865381)

抗原

See all HSD17B13 抗体
HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

适用

  • 62
  • 31
  • 25
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 45
  • 32
小鼠

克隆类型

  • 45
  • 32
单克隆

标记

  • 45
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This HSD17B13 antibody is un-conjugated

应用范围

  • 41
  • 25
  • 22
  • 13
  • 13
  • 12
  • 3
  • 3
  • 2
  • 1
Immunohistochemistry (IHC)

克隆位点

HSD17B13-13109
  • 抗原表位

    • 31
    • 15
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 1-200

    原理

    HSD17B13 / Hydroxysteroid 17-beta dehydrogenase 13 (NAFLD / NASH Marker) Antibody

    特异性

    Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-200) of human HSD17B13 protein (exact sequence is proprietary)

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

    别名

    HSD17B13

    背景

    7-beta hydroxysteroid dehydrogenase, 17-beta-HSD 13, hepatic retinol/retinal dehydrogenase, short chain dehydrogenase/reductase family 16C member 3, short-chain dehydrogenase/reductase 9

    Human liver, ovary, kidney, brain or bone marrow.

    分子量

    30kDa

    基因ID

    345275

    UniProt

    Q7Z5P4
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