HNF1B 抗体 (AA 1-200)
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北京 101111
Quick Overview for HNF1B 抗体 (AA 1-200) (ABIN7865451)
抗原
See all HNF1B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Hepatocyte nuclear factor 1 beta (HNF1b) / Transcription Factor 2 (TCF2) Antibody
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特异性
- HNF-1 (a and b), HNF-3 (a, b and g), HNF-4 (a and g) and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3a, HNF-3b and HNF-3g regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3a and HNF-3b have also been shown to be involved in gastrulation events such as body axis formation. HNF-4a and HNF-4g have been shown to be important for early embryo development. HNF-4a is expressed in liver, kidney, pancreas, small intestine, testis and colon, and HNF-4g is expressed in each of these tissues except liver. HNF-6 has been shown to bind to the promoter of HNF-3b, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation. Evidence suggests that HNF-6 may also be a transcriptional activator for at least 22 other hepatocyte enriched genes, including cytochrome P450 2C13 and a-1 antitrypsin.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-200) of human HNF1B protein (exact sequence is proprietary)
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亚型
- IgG2a, kappa
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anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibody
HNF1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibodyHNF1B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-HNF1 Homeobox B (HNF1B) (N-Term) antibodyHNF1B 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 159-300) antibodyHNF1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 1-557) antibodyHNF1B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibodyVerified HNF1B 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibodyHNF1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (C-Term) antibodyHNF1B 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 1-557) antibodyHNF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 43-92) antibodyHNF1B 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HNF1B (HNF1 Homeobox B (HNF1B))
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别名
- Hepatocyte nuclear factor 1 beta
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背景
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T2D, FJHN, HNF2, LFB3, RCAD, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, ADTKD3, HNF-1B, HNF1beta, HNF-1-beta
Human kidney, pancreas or liver tissue.
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分子量
- 61kDa
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基因ID
- 6928
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UniProt
- P35680
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途径
- Hormone Transport, Stem Cell Maintenance, Tube Formation
抗原
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