Recombinant GLN1 抗体 (AA 1-200)
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Quick Overview for Recombinant GLN1 抗体 (AA 1-200) (ABIN7864745)
抗原
See all GLN1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Recombinant Glutamine Synthetase / GLUL Antibody
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特异性
- Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 1-200) of human GLUL protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Glutamine Synthetase (GLN1) (AA 1-373) antibody
GLN1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamine Synthetase (GLN1) (AA 1-373) antibodyGLN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamine Synthetase (GLN1) (AA 285-373) antibodyGLN1 适用: 人, 小鼠 WB, IHC (p), ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamine Synthetase (GLN1) (AA 50-250) antibodyGLN1 适用: 人 IHC 宿主: 小鼠 Monoclonal 750M unconjugated
anti-Glutamine Synthetase (GLN1) (AA 1-373) antibodyGLN1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamine Synthetase (GLN1) (AA 1-373) antibodyGLN1 适用: 人 WB, ICC, IF, ELISA 宿主: 小鼠 Monoclonal AT8D7 unconjugated
anti-Glutamine Synthetase (GLN1) antibodyGLN1 适用: 小鼠, 大鼠 WB, IHC 宿主: 豚鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- GLN1 (Glutamine Synthetase (GLN1))
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别名
- Glutamine Synthetase
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背景
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cell proliferation-inducing protein 59, GLUL, Glutamate ammonia ligase, GS, PIG43, PIG59, Glutamate decarboxylase, glutamine synthase, Glutamine synthetase, glutamine synthetase I, Proliferation inducing protein 43, GLNA, GLNS
Human Liver or Human Brain or Y79
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分子量
- 42kDa
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基因ID
- 2752, 518525
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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