CEACAM1 抗体 (AA 1-200)
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北京 101111
Quick Overview for CEACAM1 抗体 (AA 1-200) (ABIN7858368)
抗原
See all CEACAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- CEACAM1 (CEA Cell Adhesion Molecule 1) / CD66a Antibody
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特异性
- Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-200) of human CEACAM1 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibody
CEACAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibodyCEACAM1 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 65-201) antibodyCEACAM1 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 7B9G3 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 35-433) antibodyCEACAM1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR090G unconjugated Recombinant Antibody
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 300-430) antibodyCEACAM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibodyCEACAM1 适用: 人 FACS, IHC (fro), cELISA 宿主: 小鼠 Monoclonal GM-8G5 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 35-143) antibodyCEACAM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 36-145) antibodyCEACAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 1-468) antibodyCEACAM1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 65-201) antibodyCEACAM1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4F3B2 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
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别名
- CEACAM1
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背景
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Antigen CD66, BGP-1, BGPI, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), CD66a, CEACAM1, meconium antigen 100
Human colon, liver, endometrium or hepatic carcinoma tissues. SK-MEL-28 cells.
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分子量
- 90-180kDa
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基因ID
- 634, 512682
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UniProt
- P13688
抗原
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