CD3G 抗体 (AA 1-182)
Our Local Distributor
北京 101111
Quick Overview for CD3G 抗体 (AA 1-182) (ABIN7865059)
抗原
See all CD3G 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-182
-
原理
- CD3G / CD3beta1 / TCR beta Antibody
-
特异性
- The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers: a heterodimer of g and e chains (ge), a heterodimer of d and e chains (de) and a homodimer of two z chains (zz) or a heterodimer of z and h chains (zh). The z and h chains are encoded by the same gene but differ in their carboxyl-terminal ends due to an alternative splicing event. The g, e and d chains each contain a single copy of a conserved immunoreceptor tyrosinebased activation motif (ITAM). In contrast, the z chain contains three consecutive copies of the same motif. Phosphorylated ITAMs act as docking sites for protein kinases such as ZAP-70 and Syk and are also capable of regulating their kinase activity. The crystal structure of the ZAP-70 SH2 domains bound to the z chain ITAMs has been solved.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment (around aa1-182) of human CD3G protein (exact sequence is proprietary)
-
亚型
- IgG2c, kappa
-
-
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-116) antibody
CD3G 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5B7B2 unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-116) antibodyCD3G 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B7F9 unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 138-182) antibodyCD3G 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) antibodyCD3G 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1585 unconjugated Recombinant Antibody
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) antibodyCD3G 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4260 unconjugated Recombinant Antibody
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 48-76), (N-Term) antibodyCD3G 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (Internal Region) antibodyVerified CD3G 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-111) antibodyCD3G 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (Internal Region) antibodyCD3G 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (Chain gamma), (N-Term) antibodyCD3G 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
-
别名
- CD3G
-
背景
-
CD3g antigen gamma polypeptide (TiT3 complex), CD3g molecule gamma (CD3 TCR complex), T cell antigen receptor complex gamma subunit of T3, T-cell surface glycoprotein CD3 gamma chain, T3G
Human colon|tonsil or spleen.
-
分子量
- 18-28kDa
-
基因ID
- 917, 2259
-
UniProt
- P09693
-
途径
- TCR Signaling, CXCR4-mediated Signaling Events
抗原
-
