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Recombinant Ubiquitin 抗体 (AA 1-119)

The 小鼠单克隆 anti-Ubiquitin antibody is suitable to detect Ubiquitin in samples from 人. It has been validated for WB 和 IHC.

产品编号 ABIN7865327

发货至: 中国

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Quick Overview for Recombinant Ubiquitin 抗体 (AA 1-119) (ABIN7865327)

抗原

See all Ubiquitin (Ub) 抗体

Ubiquitin (Ub)

抗体类型

Recombinant Antibody

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Ubiquitin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

RUBB-9476

Discover our top product Ub Primary Antibody

抗原表位
41

19

9

9

8

7

6

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 1-119

原理

Recombinant Ubiquitin (Autophagy Marker) Antibody

特异性

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.

纯化方法

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

免疫原

Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)

亚型

IgG2b, kappa
anti-Ubiquitin (Ub) antibody
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin (Ub) (AA 1-229) antibody
Ub 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 马, 兔 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin (Ub) (AA 1-229) antibody
Ub 适用: 人, 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D2 unconjugated

anti-Ubiquitin (Ub) (acLys27) antibody
Ub 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin (Ub) antibody (Atto 390)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 390

anti-Ubiquitin (Ub) antibody (Atto 488)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 488

anti-Ubiquitin (Ub) antibody (Atto 594)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 594

anti-Ubiquitin (Ub) antibody (APC)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal APC

anti-Ubiquitin (Ub) antibody (Biotin)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Biotin

anti-Ubiquitin (Ub) antibody (FITC)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal FITC

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

Ubiquitin (Ub)

别名

Ubiquitin

背景

Epididymis secretory protein Li 50, Polyubiquitin B, RPS27A, UBA52, UBA80, UBB, UBC, UBCEP1, UBCEP2, Ubiquitin, Ubiquitin B
HeLa or Raji cells, Human Brain.

分子量

9kDa

基因ID

7314, 356190, 520348

UniProt

P62979, P62987, P62988

途径

Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway