PVALB 抗体 (AA 1-110)
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北京 101111
Quick Overview for PVALB 抗体 (AA 1-110) (ABIN7858151)
抗原
See all PVALB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-110
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原理
- Parvalbumin / PVALB Antibody
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特异性
- The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100± and ≤, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins) and the parvalbumin family members, including parvalbumin ± and parvalbumin ≤, also designated oncomodulin (OCM). Structurally and evolutionarily conserved, parvalbumin ± and OCM proteins are distinct in expression and function. Parvalbumin ±, also designated parvalbumin (PV), is most abundantly expressed in fast-contracting muscles with lower expression levels in brain and some endocrine tissues, including kidney and parathyroid. Research indicates that parvalbumin ± plays a significant role in muscle relaxation. OCM was originally thought to have expression restricted to neoplastic tissues, early embryonic cells and certain tumor cell lines. Recent research shows that OCM is also expressed and secreted by macrophages where, in the retina it binds to retinal ganglion cells (RGCs) and functions to promote axon regeneration. OCM has also been detected in the auditory sensory cells of the organ of Corti in mammals. In humans, two different loci on chromosome 7 have been identified as OCM and OCM-like (LOC4951). These genes encode proteins 109 amino acids in length which share 99 % sequence identity.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-110) of human PVALB protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Parvalbumin (PVALB) (C-Term) antibody
Verified PVALB 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Parvalbumin (PVALB) (AA 2-110) antibodyPVALB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Parvalbumin (PVALB) antibodyPVALB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Parvalbumin (PVALB) (C-Term) antibodyPVALB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parvalbumin (PVALB) (AA 1-110) antibodyPVALB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Parvalbumin (PVALB) antibodyMicroarray verified PVALB 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB572452 unconjugated
anti-Parvalbumin (PVALB) antibody (PE)PVALB 适用: 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 小鼠 Monoclonal C12 PE
anti-Parvalbumin (PVALB) antibody (PerCP)PVALB 适用: 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 小鼠 Monoclonal C12 PerCP
anti-Parvalbumin (PVALB) antibody (FITC)PVALB 适用: 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 小鼠 Monoclonal C12 FITC
anti-Parvalbumin (PVALB) antibody (HRP)PVALB 适用: 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 小鼠 Monoclonal C12 HRP
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- PVALB (Parvalbumin (PVALB))
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别名
- Parvalbumin
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背景
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PVALB, Parvalbumin alpha
Human brain or kidney.
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分子量
- 12kDa
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基因ID
- 5816, 295449
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UniProt
- P20472
抗原
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