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Recombinant HBA1 抗体 (AA 1-100)

The 小鼠 单克隆 anti-HBA1 antibody (Clone rHBA-9167) (ABIN7858108) specifically detects HBA1 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7858108
发货至: 中国
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Quick Overview for Recombinant HBA1 抗体 (AA 1-100) (ABIN7858108)

抗原

See all HBA1 抗体
HBA1 (Hemoglobin, alpha 1 (HBA1))

抗体类型

Recombinant Antibody

适用

  • 56
  • 31
  • 15
  • 2
  • 2

宿主

  • 59
  • 8
小鼠

克隆类型

  • 41
  • 26
单克隆

标记

  • 39
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This HBA1 antibody is un-conjugated

应用范围

  • 42
  • 31
  • 18
  • 17
  • 12
  • 8
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)

克隆位点

RHBA-9167
  • 抗原表位

    • 14
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-100

    原理

    Recombinant Hemoglobin alpha (2 chain) Antibody

    特异性

    Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The ± (16p13.3; 5'-é 79oΩ-pseudoé 79oΩ-pseudo±2-pseudo±1-±2-±1- é 79oΩ1-3') and ≤ (11p15.5) globin loci determine the basic Hgb structure. The globin portion of Hgb consists of two ± chains and two ≤ chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between ± and ≤ chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the ±1-≤2 cleavage plane. When the two ±1-≤2 interfaces are closely bound, Hgb has a low affinity for oxygen. Hb A, which contains two ± chains plus two ≤ chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two ± chains plus two d chains, and fetal hemoglobin (Hb F), which consists of two ± chains together with two g chains.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-100) of human HBA2 protein (exact sequence is proprietary)

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    HBA1 (Hemoglobin, alpha 1 (HBA1))

    别名

    Hemoglobin alpha

    背景

    Alpha 1 globin, HBA1, HBA2, Hemoglobin alpha 1 globin chain, Hemoglobin alpha 2, Hemoglobin subunit alpha

    Human spleen, stomach cancer, lung or placenta.

    分子量

    16kDa

    基因ID

    3039, 449630

    UniProt

    P69905
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