Recombinant HBA1 抗体 (AA 1-100)
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Quick Overview for Recombinant HBA1 抗体 (AA 1-100) (ABIN7864747)
抗原
See all HBA1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- Recombinant Hemoglobin alpha (2 chain) Antibody
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特异性
- Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The ± (16p13.3; 5'-é 79oΩ-pseudoé 79oΩ-pseudo±2-pseudo±1-±2-±1- é 79oΩ1-3') and ≤ (11p15.5) globin loci determine the basic Hgb structure. The globin portion of Hgb consists of two ± chains and two ≤ chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between ± and ≤ chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the ±1-≤2 cleavage plane. When the two ±1-≤2 interfaces are closely bound, Hgb has a low affinity for oxygen. Hb A, which contains two ± chains plus two ≤ chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two ± chains plus two d chains, and fetal hemoglobin (Hb F), which consists of two ± chains together with two g chains.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-100) of human HBA2 protein (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HBA1 (Hemoglobin, alpha 1 (HBA1))
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别名
- Hemoglobin alpha
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背景
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Alpha 1 globin, HBA1, HBA2, Hemoglobin alpha 1 globin chain, Hemoglobin alpha 2, Hemoglobin subunit alpha
Human spleen, stomach cancer, lung or placenta.
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分子量
- 16kDa
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基因ID
- 3039, 449630
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UniProt
- P69905
抗原
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