Recombinant Glucagon 抗体 (AA 1-100)
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Quick Overview for Recombinant Glucagon 抗体 (AA 1-100) (ABIN7865423)
抗原
See all Glucagon (GCG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- Recombinant Glucagon (Marker of Glucagonoma) Antibody
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特异性
- Glucagon is a pancreatic hormone that functions as an antagonist to Insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the Glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone. Glucagon antibody detects glucagon-secreting cells and tumors such as glucagonomas, of which approximately 80 % are malignant.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-100) of human GCG protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Glucagon (GCG) (AA 119-148), (C-Term) antibody
GCG 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19525 unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 WB, IHC, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 21-180) antibodyGCG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Glucagon (GCG) (AA 1-180) antibodyGCG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2-E6 unconjugated
anti-Glucagon (GCG) (AA 25-54), (N-Term) antibodyGCG 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19443 unconjugated
anti-Glucagon (GCG) (AA 53-81), (N-Term) antibodyGCG 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 53-81) antibodyGCG 适用: 人, 大鼠, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 23-180) antibodyGCG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 1-180) antibodyGCG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Glucagon (GCG)
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别名
- Glucagon
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背景
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GLP1, GLP2, GRPP, GLP-1
Human pancreas.
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分子量
- 19kDa (Proglucagon), 3kDa (Glucagon)
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基因ID
- 2641
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UniProt
- P01275
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途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
抗原
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