Recombinant E2F4 抗体 (AA 1-100)
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Quick Overview for Recombinant E2F4 抗体 (AA 1-100) (ABIN7858102)
抗原
See all E2F4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- Recombinant E2F4 (Transcription Factor) Antibody
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特异性
- The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5, E2F-6 and E2F-7 each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-100) of human E2F4 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibody
E2F4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyE2F4 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 211-301) antibodyE2F4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyKD Validated E2F4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5375 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 106-144), (N-Term) antibodyE2F4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (C-Term) antibodyE2F4 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 马, 兔, 犬, Pig, 猴, 豚鼠, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 1-413) antibodyE2F4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 160-299) antibodyE2F4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyE2F4 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (acLys96) antibodyE2F4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
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别名
- E2F4
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背景
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E2F transcription factor 4, E2F transcription factor 4 p107/p130 binding, E2F-4, p107/p130 binding protein
Brain|Found in all tissue examined including heart|kidney and pancreas.|liver|lung|Placenta|skeletal muscle
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分子量
- 60kDa
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基因ID
- 1874, 108371
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UniProt
- Q16254
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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